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Triggered drug release from superhydrophobic meshes using high-intensity focused ultrasound.

ABSTRACT: Application of high-intensity focused ultrasound to drug-loaded superhydrophobic meshes affords triggered drug release by displacing an entrapped air layer. The air layer within the superhydrophobic meshes is characterized using direct visualization and B-mode imaging. Drug-loaded superhydrophobic meshes are cytotoxic in an in vitro assay after ultrasound treatment.

SUBMITTER: Yohe ST 

PROVIDER: S-EPMC3923359 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature

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Triggered drug release from superhydrophobic meshes using high-intensity focused ultrasound.

Yohe Stefan T ST   Kopechek Jonathan A JA   Porter Tyrone M TM   Colson Yolonda L YL   Grinstaff Mark W MW  

Advanced healthcare materials 20130417 9

Application of high-intensity focused ultrasound to drug-loaded superhydrophobic meshes affords triggered drug release by displacing an entrapped air layer. The air layer within the superhydrophobic meshes is characterized using direct visualization and B-mode imaging. Drug-loaded superhydrophobic meshes are cytotoxic in an in vitro assay after ultrasound treatment. ...[more]

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