Dataset Information

Respiratory-gated MRgHIFU in upper abdomen using an MR-compatible in-bore digital camera.

ABSTRACT:

Objective

To demonstrate the technical feasibility and the potential interest of using a digital optical camera inside the MR magnet bore for monitoring the breathing cycle and subsequently gating the PRFS MR thermometry, MR-ARFI measurement, and MRgHIFU sonication in the upper abdomen.

Materials and methods

A digital camera was reengineered to remove its magnetic parts and was further equipped with a 7?m long USB cable. The system was electromagnetically shielded and operated inside the bore of a closed 3T clinical scanner. Suitable triggers were generated based on real-time motion analysis of the images produced by the camera (resolution 640 × 480 pixels, 30?fps). Respiratory-gated MR-ARFI prepared MRgHIFU ablation was performed in the kidney and liver of two sheep in vivo, under general anaesthesia and ventilator-driven forced breathing.

Results

The optical device demonstrated very good MR compatibility. The current setup permitted the acquisition of motion artefact-free and high resolution MR 2D ARFI and multiplanar interleaved PRFS thermometry (average SNR 30 in liver and 56 in kidney). Microscopic histology indicated precise focal lesions with sharply delineated margins following the respiratory-gated HIFU sonications.

Conclusion

The proof-of-concept for respiratory motion management in MRgHIFU using an in-bore digital camera has been validated in vivo.

SUBMITTER: Auboiroux V

PROVIDER: S-EPMC3925565 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature

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Publications

Respiratory-gated MRgHIFU in upper abdomen using an MR-compatible in-bore digital camera.

Auboiroux Vincent V Petrusca Lorena L Viallon Magalie M Muller Arnaud A Terraz Sylvain S Breguet Romain R Montet Xavier X Becker Christoph D CD Salomir Rares R

BioMed research international 20140129

<h4>Objective</h4>To demonstrate the technical feasibility and the potential interest of using a digital optical camera inside the MR magnet bore for monitoring the breathing cycle and subsequently gating the PRFS MR thermometry, MR-ARFI measurement, and MRgHIFU sonication in the upper abdomen.<h4>Materials and methods</h4>A digital camera was reengineered to remove its magnetic parts and was further equipped with a 7 m long USB cable. The system was electromagnetically shielded and operated ins ...[more]

PMID: 24716196

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Project description:PurposeTo demonstrate that highly accelerated (net acceleration factor [R(net)] ? 10) acquisition techniques can be used to generate three-dimensional (3D) subsecond timing images, as well as diagnostic-quality high-spatial-resolution contrast material-enhanced (CE) renal magnetic resonance (MR) angiograms with a single split dose of contrast material.Materials and methodsAll studies were approved by the institutional review board and were HIPAA compliant; written consent was obtained from all participants. Twenty-two studies were performed in 10 female volunteers (average age, 47 years; range, 27-62 years) and six patients with renovascular disease (three women; average age, 48 years; range, 37-68 years; three men; average age, 60 years; range, 50-67 years; composite average age, 54 years; range, 38-68 years). The two-part protocol consisted of a low-dose (2 mL contrast material) 3D timing image with approximate 1-second frame time, followed by a high-spatial-resolution (1.0-1.6-mm isotropic voxels) breath-hold 3D renal MR angiogram (18 mL) over the full abdominal field of view. Both acquisitions used two-dimensional (2D) sensitivity encoding acceleration factor (R) of eight and 2D homodyne (HD) acceleration (R(HD)) of 1.4-1.8 for R(net) = R · R(HD) of 10 or higher. Statistical analysis included determination of mean values and standard deviations of image quality scores performed by two experienced reviewers with use of eight evaluation criteria.ResultsThe 2-mL 3D time-resolved image successfully portrayed progressive arterial filling in all 22 studies and provided an anatomic overview of the vasculature. Successful timing was also demonstrated in that the renal MR angiogram showed adequate or excellent portrayal of the main renal arteries in 21 of 22 studies.ConclusionTwo-dimensional acceleration techniques with R(net) of 10 or higher can be used in CE MR angiography to acquire (a) a 3D image series with 1-second frame time, allowing accurate bolus timing, and (b) a high-spatial-resolution renal angiogram.Supplemental materialhttp://radiology.rsna.org/lookup/suppl/doi:10.1148/radiol.11110242/-/DC1.

Dataset Information

Respiratory-gated MRgHIFU in upper abdomen using an MR-compatible in-bore digital camera.

Objective

Materials and methods

Results

Conclusion

Publications

Respiratory-gated MRgHIFU in upper abdomen using an MR-compatible in-bore digital camera.

Similar Datasets

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