Protein arginine methylation of non-histone proteins and its role in diseases.
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ABSTRACT:
SUBMITTER: Wei H
PROVIDER: S-EPMC3925732 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Publications
Protein arginine methylation of non-histone proteins and its role in diseases.
Wei Han H Mundade Rasika R Lange Kevin C KC Lu Tao T
Cell cycle (Georgetown, Tex.) 20131202 1
Protein arginine methyltransferases (PRMTs) are a family of enzymes that can methylate arginine residues on histones and other proteins. PRMTs play a crucial role in influencing various cellular functions, including cellular development and tumorigenesis. Arginine methylation by PRMTs is found on both nuclear and cytoplasmic proteins. Recently, there is increasing evidence regarding post-translational modifications of non-histone proteins by PRMTs, illustrating the previously unknown importance ...[more]
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