Total synthesis of stemaphylline N-oxide and related C9a-epimeric analogues.
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ABSTRACT:
SUBMITTER: Schulte ML
PROVIDER: S-EPMC3925759 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
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Total synthesis of stemaphylline N-oxide and related C9a-epimeric analogues.
Schulte Michael L ML Turlington Mark L ML Phatak Sharangdhar S SS Harp Joel M JM Stauffer Shaun R SR Lindsley Craig W CW
Chemistry (Weinheim an der Bergstrasse, Germany) 20130816 36
Winning the relay: The first total synthesis of stemaphylline N-oxide has been completed utilizing a bistandem relay ring-closing-metathesis (RRCM) strategy, necessitated by the conformation of the requisite tetraene. This effort also gave unnatural 9a-epi-stemaphylline and 9a-epi-stemaphylline N-oxide. ...[more]
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