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SLC17: a functionally diverse family of organic anion transporters.


ABSTRACT: Molecular studies have determined that the SLC17 transporters, a family of nine proteins initially implicated in phosphate transport, mediate the transport of organic anions. While their role in phosphate transport remains uncertain, it is now clear that the transport of organic anions facilitated by this family of proteins is involved in diverse processes ranging from the vesicular storage of the neurotransmitters, to urate metabolism, to the degradation and metabolism of glycoproteins.

SUBMITTER: Reimer RJ 

PROVIDER: S-EPMC3927456 | biostudies-literature | 2013 Apr-Jun

REPOSITORIES: biostudies-literature

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SLC17: a functionally diverse family of organic anion transporters.

Reimer Richard J RJ  

Molecular aspects of medicine 20130401 2-3


Molecular studies have determined that the SLC17 transporters, a family of nine proteins initially implicated in phosphate transport, mediate the transport of organic anions. While their role in phosphate transport remains uncertain, it is now clear that the transport of organic anions facilitated by this family of proteins is involved in diverse processes ranging from the vesicular storage of the neurotransmitters, to urate metabolism, to the degradation and metabolism of glycoproteins. ...[more]

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