Ontology highlight
ABSTRACT:
SUBMITTER: Hoare T
PROVIDER: S-EPMC3929525 | biostudies-literature | 2014 Mar
REPOSITORIES: biostudies-literature
Hoare Todd T Yeo Yoon Y Bellas Evangelia E Bruggeman Joost P JP Kohane Daniel S DS
Acta biomaterialia 20131221 3
The effectiveness of rheological blends of high molecular weight hyaluronic acid (HA) and low molecular weight hydroxypropyl methylcellulose (HPMC) in the prevention of peritoneal adhesions post-surgery is demonstrated. The physical mixture of the two carbohydrates increased the dwell time in the peritoneum while significantly improving the injectability of the polymer compared with HA alone. HA-HPMC treatment decreased the total adhesion area by ∼ 70% relative to a saline control or no treatmen ...[more]