Ontology highlight
ABSTRACT:
SUBMITTER: Golomb BA
PROVIDER: S-EPMC3931549 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Golomb Beatrice A BA Erickson Laura C LC Scott-Van Zeeland Ashley A AA Koperski Sabrina S Haas Richard H RH Wallace Douglas C DC Naviaux Robert K RK Lincoln Alan J AJ Reiner Gail E GE Hamilton Gavin G
Journal of child neurology 20131018 2
We sought to examine, via Phosphorus-31 magnetic resonance spectroscopy ((31)P-MRS) in a case-control design, whether bioenergetic deficits in autism spectrum disorders extend to the brain and muscle. Six cases with autism spectrum disorder with suspected mitochondrial dysfunction (age 6-18 years) and 6 age/sex-matched controls underwent (31)P magnetic resonance spectroscopy. The outcomes of focus were muscle resting phosphocreatine and intracellular pH as well as postexercise phosphocreatine re ...[more]