Ontology highlight
ABSTRACT:
SUBMITTER: Welch MD
PROVIDER: S-EPMC3933244 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Cell host & microbe 20130901 3
Intracellular pathogens have developed elaborate mechanisms to exploit the different cellular systems of their unwilling hosts to facilitate their entry, replication, and survival. In particular, a diverse range of bacteria and viruses have evolved unique strategies to harness the power of Arp2/3-mediated actin polymerization to enhance their cell-to-cell spread. In this review, we discuss how studying these pathogens has revolutionized our molecular understanding of Arp2/3-dependent actin assem ...[more]