Ontology highlight
ABSTRACT:
SUBMITTER: Katzel D
PROVIDER: S-EPMC3934820 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Kätzel Dennis D Miesenböck Gero G
PLoS biology 20140225 2
Although neocortical connectivity is remarkably stereotyped, the abundance of some wiring motifs varies greatly between cortical areas. To examine if regional wiring differences represent functional adaptations, we have used optogenetic raster stimulation to map the laminar distribution of GABAergic interneurons providing inhibition to pyramidal cells in layer 2/3 (L2/3) of adult mouse barrel cortex during sensory deprivation and recovery. Whisker trimming caused large, motif-specific changes in ...[more]