Ontology highlight
ABSTRACT:
SUBMITTER: Chen JL
PROVIDER: S-EPMC3340582 | biostudies-literature | 2012 Apr
REPOSITORIES: biostudies-literature
Chen Jerry L JL Villa Katherine L KL Cha Jae Won JW So Peter T C PT Kubota Yoshiyuki Y Nedivi Elly E
Neuron 20120401 2
A key feature of the mammalian brain is its capacity to adapt in response to experience, in part by remodeling of synaptic connections between neurons. Excitatory synapse rearrangements have been monitored in vivo by observation of dendritic spine dynamics, but lack of a vital marker for inhibitory synapses has precluded their observation. Here, we simultaneously monitor in vivo inhibitory synapse and dendritic spine dynamics across the entire dendritic arbor of pyramidal neurons in the adult ma ...[more]