Ontology highlight
ABSTRACT:
SUBMITTER: Xue Y
PROVIDER: S-EPMC3938757 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Xue Yong Y Vashisht Ajay A AA Tan Yuliang Y Su Trent T Wohlschlegel James A JA
PloS one 20140228 2
Cathepsin L, a lysosomal protein in mouse embryonic stem cells has been shown to clip the histone H3 N- terminus, an activity associated with gene activity during mouse cell development. Glutamate dehydrogenase (GDH) was also identified as histone H3 specific protease in chicken liver, which has been connected to gene expression during aging. In baker's yeast, Saccharomyces cerevisiae, clipping the histone H3 N-terminus has been associated with gene activation in stationary phase but the proteas ...[more]