Ontology highlight
ABSTRACT:
SUBMITTER: Kutateladze TG
PROVIDER: S-EPMC3938896 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Current topics in microbiology and immunology 20120101
Diverse biological processes including cell growth and survival require transient association of proteins with cellular membranes. A large number of these proteins are drawn to a bilayer through binding of their modular domains to phosphoinositide (PI) lipids. Seven PI isoforms are found to concentrate in distinct pools of intracellular membranes, and this lipid compartmentalization provides an efficient way for recruiting PI-binding proteins to specific cellular organelles. The atomic-resolutio ...[more]