Ontology highlight
ABSTRACT:
SUBMITTER: Xia Y
PROVIDER: S-EPMC3941077 | biostudies-literature | 2013 May
REPOSITORIES: biostudies-literature
Xia Yujie Y Xu Qingxing Q Wang Chi-Hwa CH Pack Daniel W DW
Journal of pharmaceutical sciences 20130325 5
Biodegradable polymer double-wall microspheres (DWMS) are promising vehicles for macromolecular therapeutics such as proteins and peptides. Using precision particle fabrication (PPF) technology, uniform DWMS with outer diameter approximately 55 μm were fabricated comprising poly(lactide-co-glycolide) cores encapsulating bovine serum albumin (BSA) and approximately 10 μm thick, drug-free, poly(lactic acid) (PLA) shells of varying PLA molecular weight. Also, monolithic single-wall microspheres (SW ...[more]