Ontology highlight
ABSTRACT:
SUBMITTER: Voskoboynik M
PROVIDER: S-EPMC3944792 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Biochemistry research international 20140212
The treatment of advanced melanoma has been revolutionised in recent years with the advent of a range of new therapies. BRAF inhibitors, such as vemurafenib, have demonstrated improvements in the overall survival of patients with advanced melanoma that harbour a BRAF V600 mutation. Alongside these targeted therapies, novel immune-checkpoint inhibitors, such as ipilimumab, have also been developed and have produced similarly improved outcomes for patients. For the first time in the history of mel ...[more]