Ontology highlight
ABSTRACT:
SUBMITTER: Beauchamp EM
PROVIDER: S-EPMC3946067 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Beauchamp Ellen M EM Woods Brittany A BA Dulak Austin M AM Tan Li L Xu Chunxiao C Gray Nathanael S NS Bass Adam J AJ Wong Kwok-kin KK Meyerson Matthew M Hammerman Peter S PS
Molecular cancer therapeutics 20131202 2
The treatment of non-small cell lung cancer has evolved dramatically over the past decade with the adoption of widespread use of effective targeted therapies in patients with distinct molecular alterations. In lung squamous cell carcinoma (lung SqCC), recent studies have suggested that DDR2 mutations are a biomarker for therapeutic response to dasatinib and clinical trials are underway testing this hypothesis. Although targeted therapeutics are typically quite effective as initial therapy for pa ...[more]