Modulation of raft domains in a lipid bilayer by boundary-active curcumin.
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ABSTRACT:
SUBMITTER: Tsukamoto M
PROVIDER: S-EPMC3947710 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Publications
Modulation of raft domains in a lipid bilayer by boundary-active curcumin.
Tsukamoto Manami M Kuroda Kenichi K Ramamoorthy Ayyalusamy A Yasuhara Kazuma K
Chemical communications (Cambridge, England) 20140401 26
The function and mode of action of curcumin in modulating the formation of lipid raft domains were investigated by microscopic observation using model membranes. Curcumin induces fusion of lipid raft domains at extremely low concentrations through the alteration of the boundary between the ordered and disordered phases. ...[more]
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