Increased precuneus connectivity during propofol sedation.
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ABSTRACT:
SUBMITTER: Liu X
PROVIDER: S-EPMC3959727 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Publications
Increased precuneus connectivity during propofol sedation.
Liu Xiaolin X Li Shi-Jiang SJ Hudetz Anthony G AG
Neuroscience letters 20131225
Using functional magnetic resonance imaging in human participants, we show that sedation by propofol to the point of lost overt responsiveness during the performance of an auditory verbal memory task unexpectedly increases functional connectivity of the precuneus with cortical regions, particularly the dorsal prefrontal and visual cortices. After recovery of consciousness, functional connectivity returns to a pattern similar to that observed during the wakeful baseline. In the context of a recen ...[more]
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