Ontology highlight
ABSTRACT:
SUBMITTER: Lin F
PROVIDER: S-EPMC3961564 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Lin Fubao F Zhu Jia J Tonnesen Marcia G MG Taira Breena R BR McClain Steve A SA Singer Adam J AJ Clark Richard A F RAF
The Journal of investigative dermatology 20131014 4
Stressors after injury from a multitude of factors can lead to cell death. We have identified four fibronectin (FN) peptides: two from the first FN type III repeat (FNIII1), one from the 13th FN type III repeat (FNIII13), and one from FN variable region (IIICS), which when tethered to a surface acted as platelet-derived growth factor-BB (PDGF-BB) enhancers to promote cell survival. One of the FNIII1 peptides and its smallest (14-mer) bioactive form (P12) were also active in solution. Specificall ...[more]