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Pharmacogenomics and patient care: one size does not fit all.

ABSTRACT: The time is ripe to assess whether pharmacogenomics research--the study of the genetic basis for variation in drug response--has provided important insights into a personalized approach to prescribing and dosing medications. Here, we describe the status of the field and approaches for addressing some of the open questions in pharmacogenomics research and use of genetic testing in guiding drug therapy.

SUBMITTER: Giacomini KM

PROVIDER: S-EPMC3963516 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature

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Pharmacogenomics and patient care: one size does not fit all.

Giacomini Kathleen M KM Yee Sook Wah SW Ratain Mark J MJ Weinshilboum Richard M RM Kamatani Naoyuki N Nakamura Yusuke Y

Science translational medicine 20120901 153

The time is ripe to assess whether pharmacogenomics research--the study of the genetic basis for variation in drug response--has provided important insights into a personalized approach to prescribing and dosing medications. Here, we describe the status of the field and approaches for addressing some of the open questions in pharmacogenomics research and use of genetic testing in guiding drug therapy. ...[more]

PMID: 23019654

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