Ontology highlight
ABSTRACT:
SUBMITTER: Agrawal P
PROVIDER: S-EPMC3964104 | biostudies-literature | 2014 Mar
REPOSITORIES: biostudies-literature
Agrawal Praveen P Kurcon Tomasz T Pilobello Kanoelani T KT Rakus John F JF Koppolu Sujeethraj S Liu Zhongyin Z Batista Bianca S BS Eng William S WS Hsu Ku-Lung KL Liang Yaxuan Y Mahal Lara K LK
Proceedings of the National Academy of Sciences of the United States of America 20140303 11
Cell surface glycans form a critical interface with the biological milieu, informing diverse processes from the inflammatory cascade to cellular migration. Assembly of discrete carbohydrate structures requires the coordinated activity of a repertoire of proteins, including glycosyltransferases and glycosidases. Little is known about the regulatory networks controlling this complex biosynthetic process. Recent work points to a role for microRNA (miRNA) in the regulation of specific glycan biosynt ...[more]