Ontology highlight
ABSTRACT:
SUBMITTER: Kasper BT
PROVIDER: S-EPMC4015186 | biostudies-literature | 2014 Mar
REPOSITORIES: biostudies-literature
Kasper Brian T BT Koppolu Sujeethraj S Mahal Lara K LK
Biochemical and biophysical research communications 20140123 4
Glycosylation is an intricate process requiring the coordinated action of multiple proteins, including glycosyltransferases, glycosidases, sugar nucleotide transporters and trafficking proteins. Work by several groups points to a role for microRNA (miRNA) in controlling the levels of specific glycosyltransferases involved in cancer, neural migration and osteoblast formation. Recent work in our laboratory suggests that miRNA are a principal regulator of the glycome, translating genomic informatio ...[more]