Ontology highlight
ABSTRACT:
SUBMITTER: Bentele K
PROVIDER: S-EPMC3964316 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
Molecular systems biology 20130618
The genetic code is degenerate; thus, protein evolution does not uniquely determine the coding sequence. One of the puzzles in evolutionary genetics is therefore to uncover evolutionary driving forces that result in specific codon choice. In many bacteria, the first 5-10 codons of protein-coding genes are often codons that are less frequently used in the rest of the genome, an effect that has been argued to arise from selection for slowed early elongation to reduce ribosome traffic jams. However ...[more]