Ontology highlight
ABSTRACT:
SUBMITTER: Wu L
PROVIDER: S-EPMC3966211 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Wu Linxi L Yu Xinwei X Feizpour Amin A Reinhard Björn M BM
Biomaterials science 20140201 2
Apoptosis evasion is a hallmark of cancer that motivates the development of novel strategies for inducing cell death in a controlled fashion. The size-compatibility of nanoparticles (NPs) with cellular components provides new opportunities for regulating cellular processes, potentially including apoptosis. We investigated the impact of the covalent attachment of epidermal growth factor (EGF) to 40 nm diameter Au NPs on cellular apoptosis levels, quantified as caspase-3 activity, in two <i>in vit ...[more]