Ontology highlight
ABSTRACT:
SUBMITTER: Trent CM
PROVIDER: S-EPMC3966699 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Trent Chad M CM Yu Shuiqing S Hu Yunying Y Skoller Nathan N Huggins Lesley A LA Homma Shunichi S Goldberg Ira J IJ
Journal of lipid research 20140203 4
The rodent heart accumulates TGs and lipid droplets during fasting. The sources of heart lipids could be either FFAs liberated from adipose tissue or FAs from lipoprotein-associated TGs via the action of lipoprotein lipase (LpL). Because circulating levels of FFAs increase during fasting, it has been assumed that albumin transported FFAs are the source of lipids within heart lipid droplets. We studied mice with three genetic mutations: peroxisomal proliferator-activated receptor α deficiency, cl ...[more]