Ontology highlight
ABSTRACT:
SUBMITTER: Celia C
PROVIDER: S-EPMC3970317 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Celia Christian C Ferrati Silvia S Bansal Shyam S van de Ven Anne L AL Ruozi Barbara B Zabre Erika E Hosali Sharath S Paolino Donatella D Sarpietro Maria Grazia MG Fine Daniel D Fresta Massimo M Ferrari Mauro M Grattoni Alessandro A
Advanced healthcare materials 20130723 2
Metronomic chemotherapy supports the idea that long-term, sustained, constant administration of chemotherapeutics, currently not achievable, could be effective against numerous cancers. Particularly appealing are liposomal formulations, used to solubilize hydrophobic therapeutics and minimize side effects, while extending drug circulation time and enabling passive targeting. As liposome alone cannot survive in circulation beyond 48 h, sustaining their constant plasma level for many days is a cha ...[more]