Ontology highlight
ABSTRACT:
SUBMITTER: Latreille D
PROVIDER: S-EPMC3973350 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Latreille Daniel D Bluy Lisa L Benkirane Monsef M Kiernan Rosemary E RE
Nucleic acids research 20140106 6
The epigenome is defined as a type of information that can be transmitted independently of the DNA sequence, at the chromatin level, through post-translational modifications present on histone tails. Recent advances in the identification of histone 3 variants suggest a new model of information transmission through deposition of specific histone variants. To date, several non-centromeric histone 3 variants have been identified in mammals. Despite protein sequence similarity, specific deposition c ...[more]