Ontology highlight
ABSTRACT:
SUBMITTER: Zeminian LB
PROVIDER: S-EPMC3974320 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Zeminian Luciana Bonome LB Padovani Juliana Lara JL Corvino Sílvia Maria SM Silva Giovanni Faria GF Pardini Maria Inês de Moura Campos MI Grotto Rejane Maria Tommasini RM
Memorias do Instituto Oswaldo Cruz 20130201 1
The goal of treatment of chronic hepatitis C is to achieve a sustained virological response, which is defined as exhibiting undetectable hepatitis C virus (HCV) RNA levels in serum following therapy for at least six months. However, the current treatment is only effective in 50% of patients infected with HCV genotype 1, the most prevalent genotype in Brazil. Inhibitors of the serine protease non-structural protein 3 (NS3) have therefore been developed to improve the responses of HCV-infected pat ...[more]