The ancient microbial RIO kinases.
Ontology highlight
ABSTRACT:
SUBMITTER: LaRonde NA
PROVIDER: S-EPMC3974999 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Publications
The ancient microbial RIO kinases.
The Journal of biological chemistry 20140219 14
The RIO kinases existed before the split between Archaea and Eubacteria and are essential in eukaryotes. Although much has been elucidated in the past few years regarding the function of these proteins in eukaryotes, questions remain about their role in prokaryotes. Comparison of structure and sequence suggests that the ancient RIO kinases may have similar functional properties in prokaryotes as they do in eukaryotes. The conservation of charge distribution, functional residues, and overall stru ...[more]
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