Ontology highlight
ABSTRACT:
SUBMITTER: Zimmermann J
PROVIDER: S-EPMC3975023 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Zimmermann Jasmin J Latta Lorenz L Beck Andreas A Leidinger Petra P Fecher-Trost Claudia C Schlenstedt Gabriel G Meese Eckart E Wissenbach Ulrich U Flockerzi Veit V
The Journal of biological chemistry 20140221 14
TRPC4 proteins function as Ca(2+) conducting, non-selective cation channels in endothelial, smooth muscle, and neuronal cells. To further characterize the roles of TRPC4 in vivo, detailed information about the molecular composition of native channel complexes and their association with cellular signaling networks is needed. Therefore, a mouse brain cDNA library was searched for novel TRPC4-interacting proteins using a modified yeast two-hybrid assay. This screen identified Trans-activation Respo ...[more]