Update on differences between childhood-onset and adult-onset systemic lupus erythematosus.
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SUBMITTER: Mina R
PROVIDER: S-EPMC3978647 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
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Update on differences between childhood-onset and adult-onset systemic lupus erythematosus.
Mina Rina R Brunner Hermine I HI
Arthritis research & therapy 20130821 4
Systemic lupus erythematosus (SLE) is a complex autoimmune disease and occurs worldwide in both children and adults. The estimated annual incidence among children is 2.22/100,000 and among adults is 23.2/100,000 in the United States. There is increasing understanding about differences in disease manifestations, medication use, and disease severity between those with childhood-onset SLE as compared with adult-onset SLE. Children have a more fulminant disease onset and course than adults with SLE, ...[more]
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