Ontology highlight
ABSTRACT:
SUBMITTER: Batmanghelich NK
PROVIDER: S-EPMC3979537 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Information processing in medical imaging : proceedings of the ... conference 20130101
We propose a unified Bayesian framework for detecting genetic variants associated with a disease while exploiting image-based features as an intermediate phenotype. Traditionally, imaging genetics methods comprise two separate steps. First, image features are selected based on their relevance to the disease phenotype. Second, a set of genetic variants are identified to explain the selected features. In contrast, our method performs these tasks simultaneously to ultimately assign probabilistic me ...[more]