Ontology highlight
ABSTRACT:
SUBMITTER: Batmanghelich NK
PROVIDER: S-EPMC5364030 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Batmanghelich Nematollah K NK Dalca Adrian A Quon Gerald G Sabuncu Mert M Golland Polina P
IEEE transactions on medical imaging 20160211 7
We propose a unified Bayesian framework for detecting genetic variants associated with disease by exploiting image-based features as an intermediate phenotype. The use of imaging data for examining genetic associations promises new directions of analysis, but currently the most widely used methods make sub-optimal use of the richness that these data types can offer. Currently, image features are most commonly selected based on their relevance to the disease phenotype. Then, in a separate step, a ...[more]