Ontology highlight
ABSTRACT:
SUBMITTER: Vonnemann J
PROVIDER: S-EPMC3982133 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Vonnemann Jonathan J Beziere Nicolas N Böttcher Christoph C Riese Sebastian B SB Kuehne Christian C Dernedde Jens J Licha Kai K von Schacky Claudio C Kosanke Yvonne Y Kimm Melanie M Meier Reinhard R Ntziachristos Vasilis V Haag Rainer R
Theranostics 20140320 6
We have synthesized a targeted imaging agent for rheumatoid arthritis based on polysulfated gold nanorods. The CTAB layer on gold nanorods was first replaced with PEG-thiol and then with dendritic polyglycerolsulfate at elevated temperature, which resulted in significantly reduced cytotoxicity compared to polyanionic gold nanorods functionalized by non-covalent approaches. In addition to classical characterization methods, we have established a facile UV-VIS based BaCl2 agglomeration assay to co ...[more]