Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Q
PROVIDER: S-EPMC3982169 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Zhang Qingyu Q Liu Jie J Liu Bin B Xia Juan J Chen Nianping N Chen Xiaofeng X Cao Yi Y Zhang Chen C Lu Caijie C Li Mingyi M Zhu Runzhi R
Scientific reports 20140410
The development of antitumor chemotherapy drugs remains a key goal for oncologists, and natural products provide a vast resource for anti-cancer drug discovery. In the current study, we found that the flavonoid dihydromyricetin (DHM) exhibited antitumor activity against liver cancer cells, including primary cells obtained from hepatocellular carcinoma (HCC) patients. In contrast, DHM was not cytotoxic to immortalized normal liver cells. Furthermore, DHM treatment resulted in the growth inhibitio ...[more]