Ontology highlight
ABSTRACT:
SUBMITTER: Roland WS
PROVIDER: S-EPMC3983201 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
PloS one 20140410 4
Many (dietary) bitter compounds, e.g. flavonoids, activate bitter receptor hTAS2R39 in cell-based assays. Several flavonoids, amongst which some flavanones, are known not to activate this receptor. As certain flavanones are known to mask bitter taste sensorially, flavanones might act as bitter receptor antagonists. Fourteen flavanones were investigated for their potential to reduce activation of hTAS2R39 by epicatechin gallate (ECG), one of the main bitter compounds occurring in green tea. Three ...[more]