Ontology highlight
ABSTRACT:
SUBMITTER: Jackson RN
PROVIDER: S-EPMC3984625 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Current opinion in structural biology 20140128
Helicases utilize NTPs to modulate their binding to nucleic acids and many of these enzymes also unwind DNA or RNA duplexes in an NTP-dependent fashion. These proteins are phylogenetically related but functionally diverse, with essential roles in virtually all aspects of nucleic acid metabolism. A new class of helicases associated with RNA-guided adaptive immune systems in bacteria and archaea has recently been identified. Prokaryotes acquire resistance to invading genetic parasites by integrati ...[more]