Ontology highlight
ABSTRACT:
SUBMITTER: Ni F
PROVIDER: S-EPMC3985705 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Ni Fengyun F Chen Xiaorui X Shen Jun J Wang Qinghua Q
Biochemistry 20140128 5
Membrane fusion is involved in many fundamental cellular processes and entry of enveloped viruses into host cells. Influenza type A virus HA has long served as a paradigm for mechanistic studies of protein-mediated membrane fusion via large-scale structural rearrangements induced by acidic pH. Here we report the newly determined crystal structure of influenza B virus HA2 in the postfusion state. Together with a large number of previously determined prefusion structures of influenza A and B virus ...[more]