Ontology highlight
ABSTRACT:
SUBMITTER: Costa MJ
PROVIDER: S-EPMC3988453 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Biostatistics (Oxford, England) 20130606 4
Estimation of the period length of time-course data from cyclical biological processes, such as those driven by the circadian pacemaker, is crucial for inferring the properties of the biological clock found in many living organisms. We propose a methodology for period estimation based on spectrum resampling (SR) techniques. Simulation studies show that SR is superior and more robust to non-sinusoidal and noisy cycles than a currently used routine based on Fourier approximations. In addition, a s ...[more]