Ontology highlight
ABSTRACT:
SUBMITTER: Novembre J
PROVIDER: S-EPMC3989108 | biostudies-literature | 2008 May
REPOSITORIES: biostudies-literature
Novembre John J Stephens Matthew M
Nature genetics 20080420 5
Nearly 30 years ago, Cavalli-Sforza et al. pioneered the use of principal component analysis (PCA) in population genetics and used PCA to produce maps summarizing human genetic variation across continental regions. They interpreted gradient and wave patterns in these maps as signatures of specific migration events. These interpretations have been controversial, but influential, and the use of PCA has become widespread in analysis of population genetics data. However, the behavior of PCA for gene ...[more]