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Molecular epidemiology of merkel cell polyomavirus: evidence for geographically related variant genotypes.

ABSTRACT: Merkel cell polyomavirus (MCPyV) is linked to a cutaneous cancer mainly occurring in Caucasians. DNA from skin swabs of 255 adults, originating from the 5 continents, were subjected to MCPyV PCRs. Phylogenetic analyses demonstrate the existence of 5 major geographically related MCPyV genotypes (Europe/North America, Africa [sub-Saharan], Oceania, South America, and Asia/Japan).

SUBMITTER: Martel-Jantin C

PROVIDER: S-EPMC3993677 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature

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Molecular epidemiology of merkel cell polyomavirus: evidence for geographically related variant genotypes.

Martel-Jantin Claire C Filippone Claudia C Tortevoye Patricia P Afonso Philippe V PV Betsem Edouard E Descorps-Declere Stéphane S Nicol Jérôme T J JT Touzé Antoine A Coursaget Pierre P Crouzat Maryse M Berthet Nicolas N Cassar Olivier O Gessain Antoine A

Journal of clinical microbiology 20140212 5

Merkel cell polyomavirus (MCPyV) is linked to a cutaneous cancer mainly occurring in Caucasians. DNA from skin swabs of 255 adults, originating from the 5 continents, were subjected to MCPyV PCRs. Phylogenetic analyses demonstrate the existence of 5 major geographically related MCPyV genotypes (Europe/North America, Africa [sub-Saharan], Oceania, South America, and Asia/Japan). ...[more]

PMID: 24523477

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