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2,6-Di-chloro-9-(2',3',5'-tri-O-acetyl-?-d-ribo-furanos-yl)-9H-purine.

ABSTRACT: The title synthetic analog of purine nucleosides, C16H16Cl2N4O7, has its acetyl-ated ?-furan-ose ring in a 3'?-envelope conformation, with the corresponding C atom deviating by 0.602?(5)?Å from the rest of the ring. The planar part of the furan-ose ring forms a dihedral angle of 65.0?(1)° with the mean plane of the purine bicycle. In the crystal, mol-ecules form a three-dimensional network through multiple C-H?O and C-H?N hydrogen bonds and C-H?? interactions.

SUBMITTER: Novosjolova I

PROVIDER: S-EPMC3998279 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature

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2,6-Di-chloro-9-(2',3',5'-tri-O-acetyl-β-d-ribo-furanos-yl)-9H-purine.

Novosjolova Irina I Stepanovs Dmitrijs D Bizdēna Erika E Mishnev Anatoly A Turks Māris M

Acta crystallographica. Section E, Structure reports online 20140104 Pt 2

The title synthetic analog of purine nucleosides, C16H16Cl2N4O7, has its acetyl-ated β-furan-ose ring in a 3'β-envelope conformation, with the corresponding C atom deviating by 0.602 (5) Å from the rest of the ring. The planar part of the furan-ose ring forms a dihedral angle of 65.0 (1)° with the mean plane of the purine bicycle. In the crystal, mol-ecules form a three-dimensional network through multiple C-H⋯O and C-H⋯N hydrogen bonds and C-H⋯π interactions. ...[more]

PMID: 24764840

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