Ontology highlight
ABSTRACT:
SUBMITTER: Das C
PROVIDER: S-EPMC4004086 | biostudies-literature | 2010 Sep
REPOSITORIES: biostudies-literature
Das Chandrima C Tyler Jessica K JK Churchill Mair E A ME
Trends in biochemical sciences 20100503 9
Our genetic information is tightly packaged into a rather ingenious nucleoprotein complex called chromatin in a manner that enables it to be rapidly accessed during genomic processes. Formation of the nucleosome, which is the fundamental unit of chromatin, occurs via a stepwise process that is reversed to enable the disassembly of nucleosomes. Histone chaperone proteins have prominent roles in facilitating these processes as well as in replacing old histones with new canonical histones or histon ...[more]