Ontology highlight
ABSTRACT:
SUBMITTER: Tateosian NL
PROVIDER: S-EPMC4005967 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Tateosian Nancy L NL Pasquinelli Virginia V Hernández Del Pino Rodrigo E RE Hernández Del Pino Rodrigo E RE Ambrosi Nella N Guerrieri Diego D Pedraza-Sánchez Sigifredo S Santucci Natalia N D'Attilio Luciano L Pellegrini Joaquín J Pellegrini Joaquín J Araujo-Solis María A MA Musella Rosa M RM Palmero Domingo J DJ Hernandez-Pando Rogelio R Garcia Verónica E VE Chuluyan H Eduardo HE
The American journal of pathology 20140304 5
Interferon (IFN)-γ displays a critical role in tuberculosis (TB), modulating the innate and adaptive immune responses. Previously, we reported that secretory leukocyte protease inhibitor (SLPI) is a pattern recognition receptor with anti-mycobacterial activity against Mycobacterium tuberculosis (Mtb). Herein, we determined whether IFN-γ modulated the levels of SLPI in TB patients. Plasma levels of SLPI and IFN-γ were studied in healthy donors (HDs) and TB patients. Peripheral blood mononuclear c ...[more]