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A phage protein confers resistance to the lactococcal abortive infection mechanism AbiP.

ABSTRACT: Phage bIL66M1 is sensitive to the lactococcal abortive infection mechanism AbiP. No spontaneous AbiP-resistant variant could be obtained at a frequency of <10(-10). However, AbiP-resistant variants were readily obtained during infection with both bIL66M1 and the highly homologous AbiP-resistant phage bIL170. Gain of AbiP resistance was due to the acquisition of the e6 gene from bIL170.

SUBMITTER: Domingues S

PROVIDER: S-EPMC400618 | biostudies-literature | 2004 May

REPOSITORIES: biostudies-literature

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A phage protein confers resistance to the lactococcal abortive infection mechanism AbiP.

Domingues Susana S Chopin Alain A Ehrlich S Dusko SD Chopin Marie-Christine MC

Journal of bacteriology 20040501 10

Phage bIL66M1 is sensitive to the lactococcal abortive infection mechanism AbiP. No spontaneous AbiP-resistant variant could be obtained at a frequency of <10(-10). However, AbiP-resistant variants were readily obtained during infection with both bIL66M1 and the highly homologous AbiP-resistant phage bIL170. Gain of AbiP resistance was due to the acquisition of the e6 gene from bIL170. ...[more]

PMID: 15126495

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