-1 frameshifting at a CGA AAG hexanucleotide site is required for transposition of insertion sequence IS1222.
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ABSTRACT:
SUBMITTER: Mejlhede N
PROVIDER: S-EPMC400620 | biostudies-literature | 2004 May
REPOSITORIES: biostudies-literature
Publications
-1 frameshifting at a CGA AAG hexanucleotide site is required for transposition of insertion sequence IS1222.
Mejlhede Nina N Licznar Patricia P Prère Marie-Françoise MF Wills Norma M NM Gesteland Raymond F RF Atkins John F JF Fayet Olivier O
Journal of bacteriology 20040501 10
The discovery of programmed -1 frameshifting at the hexanucleotide shift site CGA_AAG, in addition to the classical X_XXY_YYZ heptanucleotide shift sequences, prompted a search for instances among eubacterial insertion sequence elements. IS1222 has a CGA_AAG shift site. A genetic analysis revealed that frameshifting at this site is required for transposition. ...[more]
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