Ontology highlight
ABSTRACT:
SUBMITTER: Rappe U
PROVIDER: S-EPMC4007437 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Rappe Ulrike U Schlechter Tanja T Aschoff Moritz M Hotz-Wagenblatt Agnes A Hofmann Ilse I
The Journal of biological chemistry 20140318 18
The armadillo repeat protein ARVCF is a component of adherens junctions. Similar to related proteins, such as p120-catenin and β-catenin, with known signaling functions, localization studies indicate a cytoplasmic and a nuclear pool of ARVCF. We find that ARVCF interacts with different proteins involved in mRNA-processing: the splicing factor SRSF1 (SF2/ASF), the RNA helicase p68 (DDX5), and the heterogeneous nuclear ribonucleoprotein hnRNP H2. All three proteins bind to ARVCF in an RNA-independ ...[more]