Ontology highlight
ABSTRACT:
SUBMITTER: McMeniman CJ
PROVIDER: S-EPMC4007582 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
McMeniman Conor J CJ Corfas Román A RA Matthews Benjamin J BJ Ritchie Scott A SA Vosshall Leslie B LB
Cell 20140201 5
Multiple sensory cues emanating from humans are thought to guide blood-feeding female mosquitoes to a host. To determine the relative contribution of carbon dioxide (CO2) detection to mosquito host-seeking behavior, we mutated the AaegGr3 gene, a subunit of the heteromeric CO2 receptor in Aedes aegypti mosquitoes. Gr3 mutants lack electrophysiological and behavioral responses to CO2. These mutants also fail to show CO2-evoked responses to heat and lactic acid, a human-derived attractant, suggest ...[more]