Ontology highlight
ABSTRACT:
SUBMITTER: Vacchelli E
PROVIDER: S-EPMC4008470 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Vacchelli Erika E Aranda Fernando F Eggermont Alexander A Galon Jérôme J Sautès-Fridman Catherine C Cremer Isabelle I Zitvogel Laurence L Kroemer Guido G Galluzzi Lorenzo L
Oncoimmunology 20140101 1
Accumulating evidence suggests that the clinical efficacy of selected anticancer drugs, including conventional chemotherapeutics as well as targeted anticancer agents, originates (at least in part) from their ability to elicit a novel or reinstate a pre-existing tumor-specific immune response. One of the mechanisms whereby chemotherapy can stimulate the immune system to recognize and destroy malignant cells is commonly known as immunogenic cell death (ICD). Cancer cells succumbing to ICD are de ...[more]