Ontology highlight
ABSTRACT:
SUBMITTER: Dobrev D
PROVIDER: S-EPMC4008932 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Dobrev Dobromir D Wehrens Xander H T XH
Circulation research 20140401 8
Cardiac ryanodine receptor type 2 plays a key role in excitation-contraction coupling. The ryanodine receptor type 2 channel protein is modulated by various post-translational modifications, including phosphorylation by protein kinase A and Ca(2+)/calmodulin protein kinase II. Despite extensive research in this area, the functional effects of ryanodine receptor type 2 phosphorylation remain disputed. In particular, the potential involvement of increased ryanodine receptor type 2 phosphorylation ...[more]