Ontology highlight
ABSTRACT:
SUBMITTER: Gao B
PROVIDER: S-EPMC4009449 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Gao Bin B Sun Yihua Y Zhang Junhua J Ren Yan Y Fang Rong R Han Xiangkun X Shen Lei L Liu Xin-Yuan XY Pao William W Chen Haiquan H Ji Hongbin H
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20100801 8
<h4>Introduction</h4>Somatic LKB1 mutations are found in lung adenocarcinomas at different frequencies in Caucasian and East Asian (Japanese and Korean) populations. This study was designed to characterize the frequency of LKB1 mutations, their relationship to EGFR and KRAS mutations, and their associated clinicopathologic characteristics in Chinese patients.<h4>Methods</h4>Two hundred thirty-nine lung adenocarcinomas consecutively collected from October 2007 to July 2009 were dissected into 3 t ...[more]